FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term FBbt:00110337 ID (Ontology) FBbt:00110337 (Fly Anatomy)
Definition Dopaminergic neuron whose cell body is located in the dorsolateral protocerebrum of the larval brain, lateral and posterior to the DM neurons and anterior to the DL2 cluster (Monastirioti, 1999). It is part of the CP2/3 paired primary lineage (Hartenstein et al., 2017). Some of these neurons are not yet mature upon hatching, so the number of dopaminergic cells in this cluster increases from around 6-8 per hemisphere in the first instar, reaching around 9 at later larval stages (Hartenstein et al., 2017). It persists into adulthood to become a PPL1 neuron (Hartenstein et al., 2017).[ FlyBase:FBrf0108241 FlyBase:FBrf0208252 FlyBase:FBrf0234128 ]
Also Known As "DL1 neuron" ; "dorso-lateral neuron"
Comment Dopaminergic cells were identified by double labeling with a tyrosine hydroxylase (anti-TH) antibody and a TH-GAL4 driver (FBtp0020119) (Selcho et al., 2009). Five known DL1 cell types (DAN-c1, DAN-d1, DAN-f1, DAN-g1, MBIN-e2) stated to belong to PPL1 cluster in Truman et al. (2023), as well as OAN-e1, MBIN-c1 and MBIN-c2, but unclear if these are dopaminergic.
Links to External Ontologies
VFB:FBbt_00110337
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       5
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       5
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 Full annotation statements 
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 Alleles Genes Constructs
 FBbt:00110337 (all annotations which use CV term, excluding "NOT" statements)       5      1      7
Spanning Tree (Parents/Children)
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FBbt:00001919
 |__FBbt:00052047__
FBbt:00005125      |
 |__FBbt:00052047__|
 |__FBbt:00052517__|
FBbt:00005131      |
 |__FBbt:00058216__|
FBbt:00025990      |
 |__FBbt:00025991__|
FBbt:00047097      |
 |__FBbt:00052517__|
FBbt:00058211      |
 |__FBbt:00058216__|
FBbt:00059271      |
 |__FBbt:00001366__|
FBbt:00059273      |
 |__FBbt:00052047__|
                   FBbt:00110337  84 rec.
                    |__FBbt:00110338 9 rec.
                    |__FBbt:00110339 31 rec.
                    |__FBbt:00110340 31 rec.
                    |__FBbt:00110341 16 rec.
                    |__FBbt:00110342 25 rec.
                    |__FBbt:00110343
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Is a supraesophageal ganglion neuron
anterior ectoderm derivative
larval interneuron
primary interneuron
larval dopaminergic neuron
Develops from immature dopaminergic DL1 neuron
Part of
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VFB:FBbt_00110337