FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term adult moonwalker descending neuron ID (Ontology) FBbt:00111308 (Fly Anatomy)
Definition Descending neuron whose soma is located on the midline, near the medial posterior protocerebrum of the adult brain (Bidaye et al., 2014). It arborizes bilaterally in the medial ventral protocerebrum and subesophageal zone (Bidaye et al., 2014). Axonal terminals are located in the subesophageal zone and bilaterally in the thoracic neuromeres (Bidaye et al., 2014). It is cholinergic (Cheong et al., 2024). This neuron is involved in triggering backward walking (Bidaye et al., 2014) and can do this in response to visual (Sen et al., 2017), odor (Israel et al., 2022) and mechanosensory (Dahlhoff et al., 2025) stimuli. It develops from a larval mooncrawler descending neuron (Carreira-Rosario et al., 2018). There are two of these cells per hemisphere (Bidaye et al., 2014).[ FlyBase:FBrf0224613 FlyBase:FBrf0234928 FlyBase:FBrf0239825 FlyBase:FBrf0252931 ]
Also Known As "DNp50" ; "MDN" ; "MDN neuron"
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VFB:FBbt_00111308
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 adult moonwalker descending neuron (all annotations which use CV term, excluding "NOT" statements)
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adult nervous system
 |__adult central nervous system______________
central nervous system                        |
 |__adult central nervous system______________|
neuron                                        |
 |__primary neuron____________________________|
cholinergic neuron                            |
 |__adult cholinergic neuron__________________|
adult neuron                                  |
 |__adult cholinergic neuron__________________|
adult descending neuron                       |
 |__descending neuron of the posterior brain__|
adult CNS neuron                              |
 |__descending neuron of the posterior brain__|
                                              adult moonwalker descending neuron  23 rec.
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Is a primary neuron
descending neuron of the posterior brain
adult cholinergic neuron
Develops from larval mooncrawler descending neuron
Part of adult central nervous system
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VFB:FBbt_00111308