ChEBI: Sodium fluoride is a metal fluoride salt with a Na(+) counterion. It has a role as a mutagen.NCI Thesaurus (NCIt): Sodium Fluoride is an inorganic salt of fluoride used topically or in municipal water fluoridation systems to prevent dental caries. Fluoride appears to bind to calcium ions in the hydroxyapatite of surface tooth enamel, preventing corrosion of tooth enamel by acids. This agent may also inhibit acid production by commensal oral bacteria. (NCI04)