FB2026_03 , released September 17, 2026
Chemical: lipoic acid
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General Information
Name
lipoic acid
FlyBase ID
FBch0000318
ChEBI Name
lipoic acid
ChEBI ID
CHEBI:16494
PubChem Name
alpha Lipoic acid
PubChem ID
CID:864
Chemical Structure
Chemical structure of lipoic acid
lipoic acid
InChIKey

AGBQKNBQESQNJD-UHFFFAOYSA-N

Definition (ChEBI)

ChEBI: (R)-lipoic acid is the (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties. It has a role as a prosthetic group, a nutraceutical and a cofactor. It is a lipoic acid, a member of dithiolanes, a heterocyclic fatty acid and a thia fatty acid. It derives from an octanoic acid. It is a conjugate acid of a (R)-lipoate. It is an enantiomer of a (S)-lipoic acid.

Roles Classification (ChEBI)
Comment

sodium butyrate, FSG67

(Metsla et al., 2022)
Synonyms and Secondary IDs (37)
Synonyms
1,2-dithiolane-3-pentanoic acid
(ChEBI, 2019-, PubChem, 2019-)
1,2-dithiolane-3-valeric acid
(ChEBI, 2019-)
1077-28-7
(PubChem, 2019-)
5-(1,2-Dithiolan-3-yl)pentanoic acid
(PubChem, 2019-)
5-(1,2-dithiolan-3-yl)pentanoic acid
(ChEBI, 2019-, PubChem, 2019-)
5-(1,2-dithiolan-3-yl)valeric acid
(ChEBI, 2019-)
5-(dithiolan-3-yl)valeric acid
(ChEBI, 2019-)
5-[3-(1,2-dithiolanyl)]pentanoic acid
(ChEBI, 2019-)
6,8-thioctic acid
(ChEBI, 2019-)
6,8-thiotic acid
(ChEBI, 2019-)
6-thioctic acid
(ChEBI, 2019-)
6-thiotic acid
(ChEBI, 2019-)
Acetate-replacing factor
(ChEBI, 2019-)
Biletan
(ChEBI, 2019-)
DL-alpha-Lipoic acid
(PubChem, 2019-)
Lipoic acid
(Vaccaro et al., 2020, ChEBI, 2019-)
PubChem:864
(PubChem, 2019-)
Thioctacid
(PubChem, 2019-)
Thioctansaeure
(ChEBI, 2019-)
Thioctic acid
(ChEBI, 2019-)
Thioctsaeure
(ChEBI, 2019-)
Thioktsaeure
(ChEBI, 2019-)
alpha Lipoic Acid
(PubChem, 2019-)
alpha lipoic acid
(PubChem, 2019-, Ding et al., 2018)
alpha-Lipoic acid
(ChEBI, 2019-, PubChem, 2019-)
alpha-Liponsaeure
(ChEBI, 2019-)
alpha-lipoic acid
(Vernì et al., 2026, Liu et al., 2025, ChEBI, 2019-, PubChem, 2019-)
dl-Thioctic acid
(PubChem, 2019-)
dl-alpha-lipoic acid
(PubChem, 2019-)
dl-thioctic acid
(PubChem, 2019-)
lipoic acid
(Mascolo et al., 2022, ChEBI, 2019-, PubChem, 2019-, Wang et al., 2018, Chen et al., 2014, Marzio et al., 2014, Bauer et al., 2004)
liponic acid
(ChEBI, 2019-)
pubchem:864
(PubChem, 2019-)
thioctacid
(PubChem, 2019-)
thioctic acid
(PubChem, 2019-, Terán et al., 2012)
α-lipoic acid
(Bheemaiah and Chattopadhyay, 2026, Bheemaiah and Chattopadhyay, 2026, Mukherjee et al., 2025, Chattopadhyay et al., 2024, Lescouzères and Patten, 2024, Abdu-Allah et al., 2020, Wang et al., 2018, Marzio et al., 2014)
α‐lipoic acid
(Mascolo et al., 2022)
Secondary FlyBase IDs
    References (20)