FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Chemical: citalopram
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General Information
Name
citalopram
FlyBase ID
FBch0000340
ChEBI Name
citalopram
ChEBI ID
PubChem Name
Citalopram
PubChem ID
Chemical Structure
Chemical structure of citalopram
citalopram
InChIKey
Definition (ChEBI)

ChEBI: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile is a nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group. It is a member of 2-benzofurans, a nitrile, an organofluorine compound, a cyclic ether and a tertiary amino compound. It is a conjugate base of a 3-[5-cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]-N,N-dimethylpropan-1-aminium.NCI Thesaurus (NCIt): Citalopram is a bicyclic phthalene derivative and selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic activities. Citalopram selectively inhibits the neuronal reuptake of the neurotransmitter serotonin (5-HT) in presynaptic cells in the central nervous system, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions of serotonin on its receptors. Increased serotonergic neurotransmission results in antidepressive and anxiolytic effects.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (26)
Synonyms
1,3-dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile
1-(3-(dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
59729-33-8
Bonitrile
Citadur
Citalopram
Citalopramum [INN-Latin]
PubChem:2771
[3H]Citalopram
[3h]citalopram
bonitrile
citalopram hydrobromide
citalopramum
citalopramum [inn-latin]
lu 10-171
nitalapram
pubchem:2771
rac-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
Secondary FlyBase IDs
    References (10)