FB2026_02 , released June 18, 2026
Chemical: golgicide A
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General Information
Name
golgicide A
FlyBase ID
FBch0000590
ChEBI Name
golgicide A
ChEBI ID
CHEBI:139037
PubChem Name
Golgicide A
PubChem ID
CID:25113626
Chemical Structure
Chemical structure of golgicide A
golgicide A
InChIKey

NJZHEQOUHLZCOX-FTLRAWMYSA-N

Definition (ChEBI)

ChEBI: Golgicide A is a diastereoisomeric mixture comprising racemic cis- and racemic trans-goglioside A in a 10:1 ratio. It is a potent and rapidly reversible GBF1 (Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1) inhibitor. The (3aS,4R,9bR) isomer is the most active (see Bioorg. Med. Chem. Lett., 2012, 22, 5177-5181). It has a role as a cis-Golgi ArfGEF GBF inhibitor. It contains a cis-golgicide A and a trans-golgicide A.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (22)
Synonyms
(3aR,9bS)-6,8-difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
(PubChem, 2019-)
(3ar,9bs)-6,8-difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3h-cyclopenta[c]quinoline
(PubChem, 2019-)
1139889-93-2
(PubChem, 2019-)
CHEBI:139037
(PubChem, 2019-)
CHEMBL1256685
(PubChem, 2019-)
DTXSID10893485
(PubChem, 2019-)
EX-A4744
(PubChem, 2019-)
Golgicide A
(Aggarwal et al., 2022, Portela et al., 2019, PubChem, 2019-)
Golgicide A, >=98% (HPLC)
(PubChem, 2019-)
PubChem:25113626
(PubChem, 2019-)
SCHEMBL8075106
(PubChem, 2019-)
chebi:139037
(PubChem, 2019-)
chembl1256685
(PubChem, 2019-)
dtxsid10893485
(PubChem, 2019-)
ex-a4744
(PubChem, 2019-)
golgicide A
(ChEBI, 2019-)
golgicide a
(PubChem, 2019-)
golgicide a, >=98% (hplc)
(PubChem, 2019-)
pubchem:25113626
(PubChem, 2019-)
rel-(3aR,9bS)-6,8-Difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
(PubChem, 2019-)
rel-(3ar,9bs)-6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3h-cyclopenta[c]quinoline
(PubChem, 2019-)
schembl8075106
(PubChem, 2019-)
Secondary FlyBase IDs
    References (4)