FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Chemical: dynasore
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General Information
Name
dynasore
FlyBase ID
FBch0000593
ChEBI Name
dynasore
ChEBI ID
CHEBI:132754
PubChem Name
Dynasore
PubChem ID
CID:135533054
Chemical Structure
Chemical structure of dynasore
dynasore
InChIKey

SYNDQCRDGGCQRZ-VXLYETTFSA-N

Definition (ChEBI)

ChEBI: Dynasore is a carbohydrazide resulting from the formal condensation of the hydrazone moiety of 3,4-dihydroxybenzaldehyde hydrazone with the carboxy group of 3-hydroxy-2-naphthoic acid. It is a cell-permeable, reversible noncompetitive inhibitor of the GTPase activity of dynamin 1 and 2 and Drp1 (mitochondrial), while exhibiting no significant effect against two other small GTPases, MxA and Cdc42. It has a role as an EC 3.6.5.5 (dynamin GTPase) inhibitor. It is a member of catechols, a member of naphthols, a hydrazide and a hydrazone. It derives from a 3-Hydroxy-2-naphthoate.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (23)
Synonyms
2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(3,4-dihydroxyphenyl)methylene]hydrazide
(PubChem, 2019-)
2-naphthalenecarboxylic acid, 3-hydroxy-, 2-[(3,4-dihydroxyphenyl)methylene]hydrazide
(PubChem, 2019-)
3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide monohydrate
(PubChem, 2019-)
3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide
(ChEBI, 2019-)
3-hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide monohydrate
(PubChem, 2019-)
304448-55-3
(PubChem, 2019-)
ARONIS018918
(PubChem, 2019-)
CHEMBL1209885
(PubChem, 2019-)
Dynamin Inhibitor I
(ChEBI, 2019-, PubChem, 2019-)
Dynamin Inhibitor I, Dynasore
(PubChem, 2019-)
Dynasore
(Hendricks and Liebl, 2024, Kunduri and Acharya, 2024, Kim et al., 2019, Portela et al., 2019, PubChem, 2019-)
N'-(3,4-Dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide
(PubChem, 2019-)
N'-[(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide
(PubChem, 2019-)
N'-[(E)-(3,4-dihydroxyphenyl)methylene]-3-hydroxy-2-naphthohydrazide
(ChEBI, 2019-)
PubChem:135533054
(PubChem, 2019-)
aronis018918
(PubChem, 2019-)
chembl1209885
(PubChem, 2019-)
dynamin inhibitor i
(PubChem, 2019-)
dynamin inhibitor i, dynasore
(PubChem, 2019-)
dynasore
(ChEBI, 2019-, PubChem, 2019-)
n'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide
(PubChem, 2019-)
n'-[(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide
(PubChem, 2019-)
pubchem:135533054
(PubChem, 2019-)
Secondary FlyBase IDs
    References (6)