FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Chemical: latrunculin A
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General Information
Name
latrunculin A
FlyBase ID
FBch0000865
ChEBI Name
latrunculin A
ChEBI ID
CHEBI:69136
PubChem Name
Latrunculin A
PubChem ID
CID:445420
Chemical Structure
Chemical structure of latrunculin A
latrunculin A
InChIKey

DDVBPZROPPMBLW-IZGXTMSKSA-N

Definition (ChEBI)

ChEBI: Latrunculin A is a bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes. It has a role as a toxin, a metabolite and an actin polymerisation inhibitor. It is a cyclic hemiketal, an oxabicycloalkane, a thiazolidinone and a macrolide.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (24)
Synonyms
(+)-latrunculin A
(ChEBI, 2019-, PubChem, 2019-)
(+)-latrunculin a
(PubChem, 2019-)
(4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one
(ChEBI, 2019-)
76343-93-6
(PubChem, 2019-)
CHEBI:69136
(PubChem, 2019-)
LAT-A
(ChEBI, 2019-, PubChem, 2019-)
LATRUNCULIN A
(ChEBI, 2019-)
LatA
(ChEBI, 2019-, PubChem, 2019-)
Latrunculin A
(Singh et al., 2024, Nematbakhsh et al., 2020, Segal et al., 2016, Narayanareddy et al., 2014, Leibfried et al., 2013)
NSC 613011
(ChEBI, 2019-, PubChem, 2019-)
NSC613011
(PubChem, 2019-)
PubChem:445420
(PubChem, 2019-)
SRQ9WWM084
(PubChem, 2019-)
UNII-SRQ9WWM084
(PubChem, 2019-)
chebi:69136
(PubChem, 2019-)
lat-a
(PubChem, 2019-)
lata
(PubChem, 2019-)
latrunculin A
(Ermanoska et al., 2025, Schmid et al., 2024, Tam and Harris, 2024, Carim and Hickson, 2023, Qu et al., 2022, ChEBI, 2019-, Kobb et al., 2019, Bardai et al., 2018, Segal et al., 2018, Sui et al., 2018, Qu et al., 2017, Dubey et al., 2016, Segal et al., 2016, Johnson et al., 2015, Narayanareddy et al., 2014, Weil et al., 2006)
latrunculin a
(PubChem, 2019-)
nsc 613011
(PubChem, 2019-)
nsc613011
(PubChem, 2019-)
pubchem:445420
(PubChem, 2019-)
srq9wwm084
(PubChem, 2019-)
unii-srq9wwm084
(PubChem, 2019-)
Secondary FlyBase IDs
    References (23)