FB2026_03 , released September 17, 2026
Chemical: geldanamycin
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General Information
Name
geldanamycin
FlyBase ID
FBch0000903
ChEBI Name
geldanamycin
ChEBI ID
PubChem Name
Geldanamycin
PubChem ID
Chemical Structure
Chemical structure of geldanamycin
geldanamycin
InChIKey

QTQAWLPCGQOSGP-KSRBKZBZSA-N

Definition (ChEBI)

ChEBI: Geldanamycin is an ansamycin consisting of a 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. It shows antimicrobial activity against many Gram-positive and some Gram-negative bacteria. It has a role as an antiviral agent, an antineoplastic agent, an antimicrobial agent, a cysteine protease inhibitor and a Hsp90 inhibitor. It is an ansamycin, a carbamate ester, an organic heterobicyclic compound and a member of 1,4-benzoquinones.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (23)
Synonyms
(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
30562-34-6
CHEBI:5292
GELDANAMYCIN
Geldanamycin
MFCD00274570
NSC-122750
PubChem:5288382
UNII-Z3K3VJ16KU
Z3K3VJ16KU
[(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate
[(3r,5s,6r,7s,8e,10s,11s,12z,14e)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate
chebi:5292
mfcd00274570
nsc-122750
pubchem:5288382
unii-z3k3vj16ku
z3k3vj16ku
Secondary FlyBase IDs
    References (11)