FB2026_03 , released September 17, 2026
Chemical: alvespimycin
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General Information
Name
alvespimycin
FlyBase ID
FBch0000921
ChEBI Name
alvespimycin
ChEBI ID
CHEBI:65324
PubChem Name
Alvespimycin
PubChem ID
CID:5288674
Chemical Structure
Chemical structure of alvespimycin
alvespimycin
InChIKey

KUFRQPKVAWMTJO-LMZWQJSESA-N

Definition (ChEBI)

ChEBI: Alvespimycin is a 19-membered macrocyle that is geldanamycin in which the methoxy group attached to the benzoquinone moiety has been replaced by a 2-(N,N-dimethylamino)ethylamino group. It has a role as a Hsp90 inhibitor. It is a secondary amino compound, a tertiary amino compound, an ansamycin, a member of 1,4-benzoquinones and a carbamate ester. It derives from a geldanamycin.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (19)
Synonyms
(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[2-(dimethylamino)ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
(ChEBI, 2019-)
17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
(ChEBI, 2019-, PubChem, 2019-)
17-DMAG
(ChEBI, 2019-, PubChem, 2019-, Zhang et al., 2014)
17-dimethylaminoethylamino-17-demethoxygeldanamycin
(PubChem, 2019-)
17-dmag
(PubChem, 2019-)
467214-20-6
(PubChem, 2019-)
CHEBI:65324
(PubChem, 2019-)
DMAG
(PubChem, 2019-)
KOS 1022
(PubChem, 2019-)
KOS1022
(PubChem, 2019-)
PubChem:5288674
(PubChem, 2019-)
UNII-001L2FE0M3
(PubChem, 2019-)
alvespimycin
(ChEBI, 2019-, PubChem, 2019-)
chebi:65324
(PubChem, 2019-)
dmag
(PubChem, 2019-)
kos 1022
(PubChem, 2019-)
kos1022
(PubChem, 2019-)
pubchem:5288674
(PubChem, 2019-)
unii-001l2fe0m3
(PubChem, 2019-)
Secondary FlyBase IDs
    References (3)