FB2026_03 , released September 17, 2026
Chemical: lamivudine
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General Information
Name
lamivudine
FlyBase ID
FBch0001142
ChEBI Name
lamivudine
ChEBI ID
CHEBI:63577
PubChem Name
Lamivudine
PubChem ID
CID:60825
Chemical Structure
Chemical structure of lamivudine
lamivudine
InChIKey

JTEGQNOMFQHVDC-NKWVEPMBSA-N

Definition (ChEBI)

A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (28)
Synonyms
(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
(ChEBI, 2019-)
(-)-2'-Deoxy-3'-thiacytidine
(ChEBI, 2019-, PubChem, 2019-)
(-)-2'-deoxy-3'-thiacytidine
(PubChem, 2019-)
(−)-L-2′,3′-dideoxy-3′-thiacytidine
(Lin et al., 2020)
134678-17-4
(PubChem, 2019-)
2',3'-Dideoxy-3'-thiacytidine
(ChEBI, 2019-)
3'-Thia-2',3'-dideoxycytidine
(ChEBI, 2019-)
3TC
(ChEBI, 2019-, PubChem, 2019-)
3tc
(PubChem, 2019-)
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
(ChEBI, 2019-)
BCH-189
(PubChem, 2019-)
Epivir
(ChEBI, 2019-, PubChem, 2019-)
Epivir-HBV
(PubChem, 2019-)
Heptodin
(PubChem, 2019-)
Heptovir
(PubChem, 2019-)
Lamivudine
(Casale et al., 2022, ChEBI, 2019-)
PubChem:60825
(PubChem, 2019-)
Zeffix
(PubChem, 2019-)
bch-189
(PubChem, 2019-)
beta-L-2',3'-Dideoxy-3'-thiacytidine
(ChEBI, 2019-)
beta-L-3'-Thia-2',3'-dideoxycytidine
(ChEBI, 2019-)
epivir
(PubChem, 2019-)
epivir-hbv
(PubChem, 2019-)
heptodin
(PubChem, 2019-)
heptovir
(PubChem, 2019-)
lamivudine
(Iorjiim et al., 2022, Romano et al., 2020, ChEBI, 2019-, Chen-Chen et al., 2019, PubChem, 2019-)
pubchem:60825
(PubChem, 2019-)
zeffix
(PubChem, 2019-)
Secondary FlyBase IDs
    References (9)