FB2026_03 , released September 17, 2026
Chemical: ergothioneine
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General Information
Name
ergothioneine
FlyBase ID
FBch0001182
ChEBI Name
ergothioneine
ChEBI ID
CHEBI:4828
PubChem Name
Ergothioneine
PubChem ID
CID:5351619
Chemical Structure
Chemical structure of ergothioneine
ergothioneine
InChIKey

SSISHJJTAXXQAX-ZETCQYMHSA-N

Definition (ChEBI)

A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a mercapto group. A naturally occurring metabolite of histidine synthesized by bacteria and fungi with antioxidant properties. It is found ubiquitously in plants and animals and is present in many human foodstuffs.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (31)
Synonyms
(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate
(ChEBI, 2019-)
(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate
(ChEBI, 2019-)
(S)-(1-carboxy-2-(2-mercaptoimidazol-4-yl)ethyl)trimethylammonium hydroxide
(ChEBI, 2019-)
(alphaS)-alpha-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium inner salt
(ChEBI, 2019-)
2-mercaptohistidine trimethylbetaine
(ChEBI, 2019-)
3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)-2-trimethylammonio-propanoate
(ChEBI, 2019-)
497-30-3
(PubChem, 2019-)
ERGOTHIONEINE
(PubChem, 2019-)
Ergothionine
(PubChem, 2019-)
L-(+)-Ergothioneine
(PubChem, 2019-)
L-Ergothioneine
(PubChem, 2019-)
L-ergothioneine
(Tng et al., 2025, ChEBI, 2019-)
L-thioneine
(ChEBI, 2019-)
PubChem:5351619
(PubChem, 2019-)
Sympectothion
(PubChem, 2019-)
Thiolhistidine-betaine
(PubChem, 2019-)
Thioneine
(PubChem, 2019-)
UNII-BDZ3DQM98W
(PubChem, 2019-)
ergothioneine
(Tng et al., 2025, ChEBI, 2019-, PubChem, 2019-)
ergothionine
(ChEBI, 2019-, PubChem, 2019-)
erythrothioneine
(ChEBI, 2019-)
l-(+)-ergothioneine
(PubChem, 2019-)
l-Thioneine
(PubChem, 2019-)
l-ergothioneine
(PubChem, 2019-)
l-thioneine
(PubChem, 2019-)
pubchem:5351619
(PubChem, 2019-)
sympectothion
(ChEBI, 2019-, PubChem, 2019-)
thiolhistidine-betaine
(ChEBI, 2019-, PubChem, 2019-)
thiolhistidinebetaine
(ChEBI, 2019-)
thioneine
(PubChem, 2019-)
unii-bdz3dqm98w
(PubChem, 2019-)
Secondary FlyBase IDs
    References (4)