FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Chemical: donepezil
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General Information
Name
donepezil
FlyBase ID
FBch0001223
ChEBI Name
donepezil
ChEBI ID
CHEBI:53289
PubChem Name
Donepezil
PubChem ID
CID:3152
Chemical Structure
Chemical structure of donepezil
donepezil
InChIKey

ADEBPBSSDYVVLD-UHFFFAOYSA-N

Definition (ChEBI)

A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (21)
Synonyms
(S)-E2020 (free base)
(PubChem, 2019-)
(s)-e2020 (free base)
(PubChem, 2019-)
120014-06-4
(PubChem, 2019-)
2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
(PubChem, 2019-)
2-((1-benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1h-inden-1-one
(PubChem, 2019-)
2-[(1-benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
(PubChem, 2019-)
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
(PubChem, 2019-)
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1h-inden-1-one
(PubChem, 2019-)
Aricept
(PubChem, 2019-)
CHEMBL502
(PubChem, 2019-)
Donepezil
(Nguyen et al., 2021, Zhang et al., 2016)
HSDB 7743
(PubChem, 2019-)
PubChem:3152
(PubChem, 2019-)
aricept
(PubChem, 2019-)
chembl502
(PubChem, 2019-)
donepezil
(Inthachat et al., 2024, Kongsung et al., 2024, Singh et al., 2024, Singh et al., 2024, Zerva et al., 2024, Zhang et al., 2024, Mengnan et al., 2023, Ogunsuyi et al., 2023, Liu et al., 2022, Temviriyanukul et al., 2022, ChEBI, 2019-, PubChem, 2019-, Ayikobua et al., 2018, Siddique and Ali, 2017, Zhang et al., 2016, Ng et al., 2013)
donepezil hydrochloride
(Siddique and Ali, 2017)
donepezilo
(ChEBI, 2019-, PubChem, 2019-)
donepezilum
(ChEBI, 2019-)
hsdb 7743
(PubChem, 2019-)
pubchem:3152
(PubChem, 2019-)
Secondary FlyBase IDs
    References (19)