FB2026_03 , released September 17, 2026
Chemical: tanespimycin
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General Information
Name
tanespimycin
FlyBase ID
FBch0001493
ChEBI Name
tanespimycin
ChEBI ID
CHEBI:64153
PubChem Name
Tanespimycin
PubChem ID
CID:6505803
Chemical Structure
Chemical structure of tanespimycin
tanespimycin
InChIKey

AYUNIORJHRXIBJ-TXHRRWQRSA-N

Definition (ChEBI)

A 19-membered macrocyle that is geldanamycin in which the methoxy substituent attached to the benzoquinone moiety has been replaced by an allylamino group. It is a potent inhibitor of heat shock protein 90 (Hsp90). A less toxic analogue than geldanamycin, it induces apoptosis and displays antitumour effects.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (30)
Synonyms
(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
(ChEBI, 2019-)
17-(Allylamino)-17-demethoxygeldanamycin
(ChEBI, 2019-, PubChem, 2019-)
17-(Allylamino)geldanamycin
(ChEBI, 2019-, PubChem, 2019-)
17-(allylamino)-17-demethoxygeldanamycin
(PubChem, 2019-)
17-(allylamino)geldanamycin
(PubChem, 2019-)
17-AAG
(ChEBI, 2019-, PubChem, 2019-, Gregory et al., 2012)
17-Allylaminogeldanamycin
(PubChem, 2019-)
17-Demethoxy-17-allylamino geldanamycin
(ChEBI, 2019-)
17-N-allylamino-17-demethoxygeldanamycin
(ChEBI, 2019-)
17-aag
(PubChem, 2019-)
17-allylamino geldanamycin
(Gregory et al., 2012)
17-allylaminogeldanamycin
(ChEBI, 2019-, PubChem, 2019-)
17-demethoxy-17-(2-propenylamino)geldanamycin
(ChEBI, 2019-)
17AAG
(ChEBI, 2019-, PubChem, 2019-)
17aag
(PubChem, 2019-)
75747-14-7
(PubChem, 2019-)
Cp 127374
(PubChem, 2019-)
KOS-953
(PubChem, 2019-)
NSC 330507
(ChEBI, 2019-)
NSC-330507
(ChEBI, 2019-, PubChem, 2019-)
PubChem:6505803
(PubChem, 2019-)
Tanespimycin
(PubChem, 2019-)
cp 127374
(PubChem, 2019-)
kos-953
(PubChem, 2019-)
nsc-330507
(PubChem, 2019-)
pubchem:6505803
(PubChem, 2019-)
tanespimycin
(ChEBI, 2019-, PubChem, 2019-)
tanespimycina
(ChEBI, 2019-)
tanespimycine
(ChEBI, 2019-)
tanespimycinum
(ChEBI, 2019-)
Secondary FlyBase IDs
    References (3)