FB2026_02 , released June 18, 2026
Chemical: fasudil
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General Information
Name
fasudil
FlyBase ID
FBch0001504
ChEBI Name
fasudil
ChEBI ID
CHEBI:43871
PubChem Name
Fasudil
PubChem ID
CID:3547
Chemical Structure
Chemical structure of fasudil
fasudil
InChIKey

NGOGFTYYXHNFQH-UHFFFAOYSA-N

Definition (ChEBI)

An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (25)
Synonyms
1-(5-isoquinolinesulfonyl)homopiperazine
(ChEBI, 2019-)
103745-39-7
(PubChem, 2019-)
1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-
(PubChem, 2019-)
1h-1,4-diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-
(PubChem, 2019-)
5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
(ChEBI, 2019-, PubChem, 2019-)
5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]isoquinoline
(ChEBI, 2019-)
AT 877
(ChEBI, 2019-, PubChem, 2019-)
AT-877
(ChEBI, 2019-, PubChem, 2019-)
Fasudil
(PubChem, 2019-, Gentry et al., 2016)
Fasudilum
(PubChem, 2019-)
HA 1077
(ChEBI, 2019-, PubChem, 2019-)
HA-1077
(ChEBI, 2019-)
HA1077
(ChEBI, 2019-, PubChem, 2019-)
PubChem:3547
(PubChem, 2019-)
ZK-258594
(ChEBI, 2019-)
at 877
(PubChem, 2019-)
at-877
(PubChem, 2019-)
fasudil
(ChEBI, 2019-, PubChem, 2019-, Llavero Hurtado et al., 2017, Spindler et al., 2012)
fasudilum
(ChEBI, 2019-, PubChem, 2019-)
ha 1077
(PubChem, 2019-)
ha-1077
(PubChem, 2019-)
ha1077
(PubChem, 2019-)
hexahydro-1-(5-isoquinolinesulfonyl)-1H-1,4-diazepine
(ChEBI, 2019-)
hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine
(ChEBI, 2019-)
pubchem:3547
(PubChem, 2019-)
Secondary FlyBase IDs
    References (5)