FB2026_03 , released September 17, 2026
Chemical: U-73122
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General Information
Name
U-73122
FlyBase ID
FBch0001735
ChEBI Name
U-73122
ChEBI ID
CHEBI:90690
PubChem Name
1-(6-(((17beta)-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione
PubChem ID
CID:104794
Chemical Structure
Chemical structure of U-73122
U-73122
InChIKey

LUFAORPFSVMJIW-ZRJUGLEFSA-N

Definition (ChEBI)

An aza-steroid that is 3-O-methyl-17beta-estradiol in which the 17beta-hydroxy group is replaced by a 6-(maleimid-1-yl)hexylamino group. An inibitor of phospholipase C. ChEBI: U-73122 is an aza-steroid that is 3-O-methyl-17beta-estradiol in which the 17beta-hydroxy group is replaced by a 6-(maleimid-1-yl)hexylamino group. An inibitor of phospholipase C. It has a role as an EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor. It is an aza-steroid, a member of maleimides and an aromatic ether. It is functionally related to a 17beta-estradiol.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (22)
Synonyms
1-(6-((3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione
(ChEBI, 2019-, PubChem, 2019-)
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1h-pyrrole-2,5-dione
(PubChem, 2019-)
1-(6-{[(17beta)-3-methoxyestra-1(10),2,4-trien-17-yl]amino}hexyl)-1H-pyrrole-2,5-dione
(ChEBI, 2019-)
1-[6-[[(8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]amino]hexyl]pyrrole-2,5-dione
(PubChem, 2019-)
1-[6-[[(8r,9s,13s,14s,17s)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]amino]hexyl]pyrrole-2,5-dione
(PubChem, 2019-)
112648-68-7
(PubChem, 2019-)
CHEBI:90690
(PubChem, 2019-)
CHEMBL1256678
(PubChem, 2019-)
PubChem:104794
(PubChem, 2019-)
U 73122
(ChEBI, 2019-, PubChem, 2019-)
U-73,122
(ChEBI, 2019-, PubChem, 2019-)
U-73122
(Gao et al., 2022, ChEBI, 2019-, PubChem, 2019-, Rajan et al., 2017, Getahun et al., 2013)
U-73122 hydrate
(PubChem, 2019-)
U73122
(Blaum et al., 2025, Lee et al., 2024, Gao et al., 2022, Oh et al., 2019, PubChem, 2019-, Rajan et al., 2017, Getahun et al., 2013)
chebi:90690
(PubChem, 2019-)
chembl1256678
(PubChem, 2019-)
pubchem:104794
(PubChem, 2019-)
u 73122
(PubChem, 2019-)
u-73,122
(PubChem, 2019-)
u-73122
(PubChem, 2019-)
u-73122 hydrate
(PubChem, 2019-)
u73122
(PubChem, 2019-)
Secondary FlyBase IDs
    References (8)