FB2026_03 , released September 17, 2026
Chemical: leupeptin
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General Information
Name
leupeptin
FlyBase ID
FBch0001745
ChEBI Name
leupeptin
ChEBI ID
CHEBI:6426
PubChem Name
Leupeptin
PubChem ID
CID:72429
Chemical Structure
Chemical structure of leupeptin
leupeptin
InChIKey

GDBQQVLCIARPGH-ULQDDVLXSA-N

Definition (ChEBI)

A tripeptide composed of N-acetylleucyl, leucyl and argininal residues joined in sequenceby peptide linkages. It is an inhibitor of the calpains, a family of calcium-activated proteases which promote cell death.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (26)
Synonyms
(2S)-2-acetamido-N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
(PubChem, 2019-)
(2s)-2-acetamido-n-[(2s)-1-[[(2s)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
(PubChem, 2019-)
103476-89-7
(PubChem, 2019-)
24365-47-7
(PubChem, 2019-)
55123-66-5
(PubChem, 2019-)
Ac-L-Leu-L-Leu-L-Arg-H
(ChEBI, 2019-)
Ac-LLR-H
(ChEBI, 2019-)
Ac-Leu-Leu-Arg-H
(ChEBI, 2019-, PubChem, 2019-)
Ac-Leu-Leu-Argininal
(PubChem, 2019-)
Ac-Leu-Leu-argininal
(ChEBI, 2019-)
CHEBI:6426
(PubChem, 2019-)
J97339NR3V
(PubChem, 2019-)
Leupeptin
(PubChem, 2019-)
Leupeptin hemisulfate
(PubChem, 2019-)
N-acetyl-L-leucyl-L-leucyl-L-argininal
(ChEBI, 2019-)
N-acetyl-L-leucyl-N-[(2S)-5-carbamimidamido-1-oxopentan-2-yl]-L-leucinamide
(ChEBI, 2019-)
N-acetyl-leucylleucylargininal
(ChEBI, 2019-)
PubChem:72429
(PubChem, 2019-)
ac-leu-leu-arg-h
(PubChem, 2019-)
ac-leu-leu-argininal
(PubChem, 2019-)
acetyl-L-leucyl-L-leucyl-L-argininal
(ChEBI, 2019-)
chebi:6426
(PubChem, 2019-)
j97339nr3v
(PubChem, 2019-)
leupeptin
(Gatti et al., 2024, ChEBI, 2019-, PubChem, 2019-, Ping et al., 2015)
leupeptin hemisulfate
(PubChem, 2019-)
pubchem:72429
(PubChem, 2019-)
Secondary FlyBase IDs
    References (4)