FB2026_03 , released September 17, 2026
Chemical: LRRK2-IN-1
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General Information
Name
LRRK2-IN-1
FlyBase ID
FBch0001815
ChEBI Name
LRRK2-IN-1
ChEBI ID
CHEBI:78413
PubChem Name
Lrrk2-IN-1
PubChem ID
CID:46843906
Chemical Structure
Chemical structure of LRRK2-IN-1
LRRK2-IN-1
InChIKey

IWMCPJZTADUIFX-UHFFFAOYSA-N

Definition (ChEBI)

A member of the class of pyrimidobenzodiazepines that is 5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one carrying at C-2 on the pyrimidine ring a 4-[(4-methylpiperazin-1-yl)piperidine-1-carbonyl]-2-methoxyanilino substituent. It is an inhibitor of the Parkinson's disease kinase LRRK2.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (21)
Synonyms
1234480-84-2
(PubChem, 2019-)
2-((2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenyl)-amino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one
(PubChem, 2019-)
2-((2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenyl)amino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one
(PubChem, 2019-)
2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenyl)-amino)-5,11-dimethyl-5h-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11h)-one
(PubChem, 2019-)
2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenyl)amino)-5,11-dimethyl-5h-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11h)-one
(PubChem, 2019-)
2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
(ChEBI, 2019-)
2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one
(PubChem, 2019-)
5,11-Dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
(PubChem, 2019-)
5,11-dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dimethyl-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one
(PubChem, 2019-)
CHEBI:78413
(PubChem, 2019-)
CHEMBL2012582
(PubChem, 2019-)
LRRK2-IN-1
(ChEBI, 2019-, PubChem, 2019-, Cording et al., 2017, Afsari et al., 2014)
LRRK2-IN1
(ChEBI, 2019-, PubChem, 2019-)
LRRK2IN1
(ChEBI, 2019-, PubChem, 2019-)
PubChem:46843906
(PubChem, 2019-)
chebi:78413
(PubChem, 2019-)
chembl2012582
(PubChem, 2019-)
lrrk2-in-1
(PubChem, 2019-)
lrrk2-in1
(PubChem, 2019-)
lrrk2in1
(PubChem, 2019-)
pubchem:46843906
(PubChem, 2019-)
Secondary FlyBase IDs
    References (4)