FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Chemical: TAK-733
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General Information
Name
TAK-733
FlyBase ID
FBch0001885
ChEBI Name
TAK-733
ChEBI ID
CHEBI:231366
PubChem Name
Tak-733
PubChem ID
CID:24963252
Chemical Structure
Chemical structure of TAK-733
TAK-733
InChIKey

RCLQNICOARASSR-SECBINFHSA-N

Definition (ChEBI)

A member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione substituted by (2R)-2,3-dihydroxypropyl, (2-fluoro-4-iodophenyl)amino, fluoro, and methyl groups at positions 3, 5, 6, and 8, respectively. It is a non-ATP competitive allosteric inhibitor of MEK1/2.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (21)
Synonyms
(R)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione
(ChEBI, 2019-, PubChem, 2019-, Albert and Bökel, 2017)
(r)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3h,8h)-dione
(PubChem, 2019-)
1035555-63-5
(PubChem, 2019-)
3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-(2-fluoro-4-iodoanilino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione
(ChEBI, 2019-)
3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodo-phenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidine-4,7-dione
(ChEBI, 2019-)
3-[(2r)-2,3-Dihydroxypropyl]-6-Fluoro-5-[(2-Fluoro-4-Iodophenyl)amino]-8-Methylpyrido[2,3-D]pyrimidine-4,7(3h,8h)-Dione
(PubChem, 2019-)
3-[(2r)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methylpyrido[2,3-d]pyrimidine-4,7(3h,8h)-dione
(PubChem, 2019-)
5J61HSP0QJ
(PubChem, 2019-)
5j61hsp0qj
(PubChem, 2019-)
CHEMBL1615025
(PubChem, 2019-)
Mek inhibitor tak-733
(PubChem, 2019-)
TAK 733
(ChEBI, 2019-, PubChem, 2019-)
TAK-733
(PubChem, 2019-, Albert and Bökel, 2017)
TAK733
(ChEBI, 2019-, PubChem, 2019-)
UNII-5J61HSP0QJ
(PubChem, 2019-)
chembl1615025
(PubChem, 2019-)
mek inhibitor tak-733
(PubChem, 2019-)
tak 733
(PubChem, 2019-)
tak-733
(PubChem, 2019-, Albert and Bökel, 2017)
tak733
(PubChem, 2019-)
unii-5j61hsp0qj
(PubChem, 2019-)
Secondary FlyBase IDs
    References (3)