FB2026_03 , released September 17, 2026
Chemical: tubastatin A
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General Information
Name
tubastatin A
FlyBase ID
FBch0001941
ChEBI Name
tubastatin A
ChEBI ID
CHEBI:94186
PubChem Name
Tubastatin A
PubChem ID
CID:49850262
Chemical Structure
Chemical structure of tubastatin A
tubastatin A
InChIKey

GOVYBPLHWIEHEJ-UHFFFAOYSA-N

Definition (ChEBI)

A pyridoindole that is 1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indole which is substituted on the tetrahydropyridine nitrogen by a methyl group and on the indole nitrogen by a p-[N-(hydroxy)aminocarbonyl]benzyl group. It is a histone deacetylase 6 (HDAC6) inhibitor that is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (23)
Synonyms
1252003-15-8
(PubChem, 2019-)
2XTSOX1NF8
(PubChem, 2019-)
2xtsox1nf8
(PubChem, 2019-)
N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide
(PubChem, 2019-)
N-hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide
(ChEBI, 2019-)
N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide
(ChEBI, 2019-, PubChem, 2019-)
PubChem:49850262
(PubChem, 2019-)
Tubastatin A
(PubChem, 2019-)
Tubastatin A (free base)
(PubChem, 2019-)
Tubastatin A (trifluoroacetate)
(PubChem, 2019-)
Tubastatin A BASE
(PubChem, 2019-)
Tubastatin A(free base)
(PubChem, 2019-)
Tubastatin-A
(PubChem, 2019-)
n-hydroxy-4-((2-methyl-3,4-dihydro-1h-pyrido[4,3-b]indol-5(2h)-yl)methyl)benzamide
(PubChem, 2019-)
n-hydroxy-4-[(2-methyl-3,4-dihydro-1h-pyrido[4,3-b]indol-5-yl)methyl]benzamide
(PubChem, 2019-)
pubchem:49850262
(PubChem, 2019-)
tubastatin A
(ChEBI, 2019-, Mao et al., 2017)
tubastatin a
(PubChem, 2019-)
tubastatin a (free base)
(PubChem, 2019-)
tubastatin a (trifluoroacetate)
(PubChem, 2019-)
tubastatin a base
(PubChem, 2019-)
tubastatin a(free base)
(PubChem, 2019-)
tubastatin-a
(ChEBI, 2019-, PubChem, 2019-)
Secondary FlyBase IDs
    References (3)