FB2026_03 , released September 17, 2026
Chemical: rigosertib
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General Information
Name
rigosertib
FlyBase ID
FBch0002038
ChEBI Name
rigosertib
ChEBI ID
CHEBI:145417
PubChem Name
Rigosertib
PubChem ID
CID:6918736
Chemical Structure
Chemical structure of rigosertib
rigosertib
InChIKey

OWBFCJROIKNMGD-BQYQJAHWSA-N

Definition (ChEBI)

An N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine in which the double bond has E-configuration. It is a non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM and exhibits anti-cancer properties.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (26)
Synonyms
(E)-2-((2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenyl)amino)acetic acid
(PubChem, 2019-)
(E)-ON 01910
(ChEBI, 2019-)
(e)-2-((2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenyl)amino)acetic acid
(PubChem, 2019-)
2-[2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]anilino]acetic acid
(PubChem, 2019-)
2-[2-methoxy-5-[[(e)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]anilino]acetic acid
(PubChem, 2019-)
592542-59-1
(PubChem, 2019-)
67DOW7F9GL
(PubChem, 2019-)
67dow7f9gl
(PubChem, 2019-)
N-[2-Methoxy-5-({[(E)-2-(2,4,6-Trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine
(PubChem, 2019-)
N-[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine
(ChEBI, 2019-)
ON 01910
(ChEBI, 2019-, PubChem, 2019-)
ON-01910
(ChEBI, 2019-, PubChem, 2019-)
ON01910
(Mao et al., 2016)
PubChem:6918736
(PubChem, 2019-)
Rigosertib
(PubChem, 2019-)
Rigosertib (USAN)
(PubChem, 2019-)
Rigosertib [USAN]
(PubChem, 2019-)
[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)anilino]acetic acid
(ChEBI, 2019-)
n-[2-methoxy-5-({[(e)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine
(PubChem, 2019-)
on 01910
(PubChem, 2019-)
on-01910
(PubChem, 2019-)
pubchem:6918736
(PubChem, 2019-)
rigosertib
(ChEBI, 2019-, PubChem, 2019-, Mao et al., 2016)
rigosertib (usan)
(PubChem, 2019-)
rigosertib [usan]
(PubChem, 2019-)
rigosertibum
(ChEBI, 2019-)
Secondary FlyBase IDs
    References (3)