FB2026_03 , released September 17, 2026
Chemical: Z-Val-Ala-Asp(OMe)-CH2F
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General Information
Name
Z-Val-Ala-Asp(OMe)-CH2F
FlyBase ID
FBch0002039
ChEBI Name
Z-Val-Ala-Asp(OMe)-CH2F
ChEBI ID
CHEBI:137045
PubChem Name
Z-VAD-fmk
PubChem ID
CID:5497174
Chemical Structure
Chemical structure of Z-Val-Ala-Asp(OMe)-CH2F
Z-Val-Ala-Asp(OMe)-CH2F
InChIKey

MIFGOLAMNLSLGH-SXUUOERCSA-N

MIFGOLAMNLSLGH-QOKNQOGYSA-N

Definition (ChEBI)

A tripeptide consisting of Z-Val-Ala-Asp(OMe) in which the C-terminal OH group has been replaced by a fluoromethyl group. An irreversible pan-caspase inhibitor. ChEBI: Z-Val-Ala-Asp(OMe)-CH2F is a tripeptide consisting of Z-Val-Ala-Asp(OMe) in which the C-terminal OH group has been replaced by a fluoromethyl group. An irreversible pan-caspase inhibitor. It has a role as an apoptosis inhibitor and a protease inhibitor. It is a carbamate ester, a tripeptide and an organofluorine compound.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (16)
Synonyms
187389-52-2
(PubChem, 2019-)
5-Bromo-2 -deoxyuridine
(PubChem, 2019-)
C22H30FN3O7
(PubChem, 2019-)
N-[(benzyloxy)carbonyl]-L-valyl-N-[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]-L-alaninamide
(ChEBI, 2019-)
PubChem:5497174
(PubChem, 2019-)
Z-L-Val-L-Ala-L-Asp(OMe)-CH2F
(ChEBI, 2019-)
Z-VAD (OMe)-FMK
(PubChem, 2019-)
Z-VAD(OMe)-FMK
(ChEBI, 2019-, PubChem, 2019-)
Z-VAD-FMK
(ChEBI, 2019-)
Z-Val-Ala-Asp(OMe)-CH2F
(PubChem, 2019-, Mao et al., 2016)
Z-Val-Ala-Asp(OMe)-FMK
(ChEBI, 2019-, PubChem, 2019-)
Z-Val-Ala-Asp(OMe)-fluoromethyl ketone
(ChEBI, 2019-, PubChem, 2019-)
ZVAD-FMK
(PubChem, 2019-)
methyl 5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoate
(PubChem, 2019-, Mao et al., 2016)
pan-caspase inhibitor
(ChEBI, 2019-, PubChem, 2019-)
z-VAD-fmk
(Mao et al., 2016)
Secondary FlyBase IDs
    References (3)