FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Chemical: erastin
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General Information
Name
erastin
FlyBase ID
FBch0002041
ChEBI Name
erastin
ChEBI ID
CHEBI:94287
PubChem Name
Erastin
PubChem ID
CID:11214940
Chemical Structure
Chemical structure of erastin
erastin
InChIKey

BKQFRNYHFIQEKN-UHFFFAOYSA-N

Definition (ChEBI)

A member of the class of quinazolines that is quinazolin-4(3H)-one in which the hydrogens at positions 2 and 3 are replaced by 1-{4-[(4-chlorophenoxy)acetyl]piperazin-1-yl}ethyl and 2-ethoxyphenyl groups, respectively. It is an inhibitor of voltage-dependent anion-selective channels (VDAC2 and VDAC3) and a potent ferroptosis inducer.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (22)
Synonyms
2-(1-(4-(2-(4-Chlorophenoxy)acetyl)-1-piperazinyl)ethyl)-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
(PubChem, 2019-)
2-(1-(4-(2-(4-Chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4-one
(PubChem, 2019-)
2-(1-(4-(2-(4-chlorophenoxy)acetyl)-1-piperazinyl)ethyl)-3-(2-ethoxyphenyl)-4(3h)-quinazolinone
(PubChem, 2019-)
2-(1-(4-(2-(4-chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one
(PubChem, 2019-)
2-(1-(4-(2-(4-chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3h)-one
(PubChem, 2019-)
2-(1-(4-(2-(4-chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4-one
(PubChem, 2019-)
2-(1-{4-[(4-chlorophenoxy)acetyl]piperazin-1-yl}ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one
(ChEBI, 2019-)
2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone
(PubChem, 2019-)
2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
(ChEBI, 2019-)
2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3h)-quinazolinone
(PubChem, 2019-)
2-[1-[4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one
(PubChem, 2019-)
571203-78-6
(PubChem, 2019-)
CHEMBL401989
(PubChem, 2019-)
ERASTIN
(PubChem, 2019-)
MFCD09837984
(PubChem, 2019-)
PubChem:11214940
(PubChem, 2019-)
ZJA3NS42T9
(PubChem, 2019-)
chembl401989
(PubChem, 2019-)
erastin
(Agostini et al., 2023, ChEBI, 2019-, PubChem, 2019-, Wang et al., 2016)
mfcd09837984
(PubChem, 2019-)
pubchem:11214940
(PubChem, 2019-)
zja3ns42t9
(PubChem, 2019-)
Secondary FlyBase IDs
    References (4)