FB2026_03 , released September 17, 2026
Chemical: ethambutol
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General Information
Name
ethambutol
FlyBase ID
FBch0002287
ChEBI Name
ethambutol
ChEBI ID
PubChem Name
Ethambutol
PubChem ID
Chemical Structure
Chemical structure of ethambutol
ethambutol
InChIKey

AEUTYOVWOVBAKS-UWVGGRQHSA-N

Definition (ChEBI)

An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone. ChEBI: Ethambutol is an ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone. It has a role as an antitubercular agent, an environmental contaminant and a xenobiotic. It is a member of ethanolamines and an ethylenediamine derivative.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (21)
Synonyms
(+)-2,2'-(ethylenediimino)di-1-butanol
(+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine
(+)-S,S-ethambutol
(+)-ethambutol
(2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol
(2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol
(S,S)-ethambutol
Aethambutolum
D-Ethambutol
Ethambutol
Ethambutol Hydrochloride
Ethambutolum
Myambutol
PubChem:14052
S,S-Ethambutol
etambutol
ethambutolum
Secondary FlyBase IDs
    References (3)