FB2026_03 , released September 17, 2026
Chemical: sonidegib
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General Information
Name
sonidegib
FlyBase ID
FBch0002636
ChEBI Name
sonidegib
ChEBI ID
PubChem Name
Sonidegib
PubChem ID
Chemical Structure
Chemical structure of sonidegib
sonidegib
InChIKey

VZZJRYRQSPEMTK-CALCHBBNSA-N

Definition (ChEBI)

A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as its phosphate salt) for treatment of locally advanced basal cell carcinoma. ChEBI: Sonidegib is a member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as its phosphate salt) for treatment of locally advanced basal cell carcinoma. It has a role as an antineoplastic agent, a SMO receptor antagonist and a Hedgehog signaling pathway inhibitor. It is a member of morpholines, an aminopyridine, a member of biphenyls, a member of benzamides, an aromatic ether, an organofluorine compound and a tertiary amino compound.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (14)
Synonyms
956697-53-3
N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
PubChem:24775005
Sonidegib
rel-N-{6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl}-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
Secondary FlyBase IDs
    References (3)