FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Chemical: IWR-1-endo
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General Information
Name
IWR-1-endo
FlyBase ID
FBch0002746
ChEBI Name
IWR-1-endo
ChEBI ID
CHEBI:62882
PubChem Name
IWR-1-endo
PubChem ID
CID:44483163
Chemical Structure
Chemical structure of IWR-1-endo
IWR-1-endo
InChIKey

ZGSXEXBYLJIOGF-ALFLXDJESA-N

Definition (ChEBI)

A dicarboximide having an endo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. ChEBI: IWR-1-endo is a dicarboximide having an endo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. It has a role as an axin stabilizer and a Wnt signalling inhibitor. It is a dicarboximide, a bridged compound, a member of quinolines and a member of benzamides.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (11)
Synonyms
1127442-82-3
(PubChem, 2019-)
4-[(3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide
(ChEBI, 2019-, PubChem, 2019-)
CHEBI:62882
(PubChem, 2019-)
CHEMBL562310
(PubChem, 2019-)
IWR-1
(Sharmin et al., 2024, PubChem, 2019-)
IWR-1 endo
(PubChem, 2019-)
IWR-1-endo
(ChEBI, 2019-, PubChem, 2019-)
PubChem:44483163
(PubChem, 2019-)
endo-IWR 1;IWR-1-endo
(PubChem, 2019-)
endo-IWR-1
(PubChem, 2019-)
rel-4-((3aR,4S,7R,7aS)-1,3-Dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)-N-(quinolin-8-yl)benzamide
(PubChem, 2019-)
Secondary FlyBase IDs
    References (3)