FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Chemical: decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone
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General Information
Name
decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone
FlyBase ID
FBch0002937
ChEBI Name
decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone
ChEBI ID
PubChem Name
decanoyl-RVKR-chloromethylketone
PubChem ID
Chemical Structure
Chemical structure of decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone
decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone
InChIKey

NHBJTTGFHCHQHS-VZTVMPNDSA-N

Definition (ChEBI)

A tetrapeptide consisting of N-decanoyl-L-arginine, L-valine, L-lysine, and L-arginine joined in sequence by peptide linkages and in which the carboxy group at the C-terminus is substituted by a chloroacetyl group. It is a furin inhibitor that has antiviral activity against Chikungunya virus, Zika virus and Japanese encephalitis virus. ChEBI: Decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone is a tetrapeptide consisting of N-decanoyl-L-arginine, L-valine, L-lysine, and L-arginine joined in sequence by peptide linkages and in which the carboxy group at the C-terminus is substituted by a chloroacetyl group. It is a furin inhibitor that has antiviral activity against Chikungunya virus, Zika virus and Japanese encephalitis virus. It has a role as an antiviral agent, a peptidomimetic and an EC 3.4.21.75 (furin) inhibitor. It is a tetrapeptide and an organochlorine compound.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (18)
Synonyms
150113-99-8
DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE
Dec-RVKR-CMK
Decanoyl-Arg-Val-Lys-Arg-chloromethylketone trifluoroacetate salt
Decanoyl-RVKR-CMK
Furin Inhibitor I
Furin inhibitor I
Furin-IN-I
N(2)-(1-oxodecyl)-L-arginyl-L-valyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-L-lysinamide
N(2)-decanoyl-L-arginyl-L-valyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-lysinamide
N-[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]decanamide
PubChem:9962075
dec-RVKR-cmk
decanoyl-Arg-Val-Lys-Arg-CMK
decanoyl-Arg-Val-Lys-Arg-chloromethyl ketone
decanoyl-Arg-Val-Lys-Arg-chloromethylketone
decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone
decanoyl-RVKR-CMK
Secondary FlyBase IDs
    References (3)