A branched-chain saturated fatty acid anion that is the conjugate base of valproic acid. California Office of Environmental Health Hazard Assessment (OEHHA): Valproate (Valproic acid) can cause developmental toxicity according to an independent committee of scientific and health experts.ChEBI: Valproate is a branched-chain saturated fatty acid anion that is the conjugate base of valproic acid. It has a role as an antimanic drug. It is functionally related to a valerate. It is a conjugate base of a valproic acid.