FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Chemical: roflumilast
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General Information
Name
roflumilast
FlyBase ID
FBch0002950
ChEBI Name
roflumilast
ChEBI ID
PubChem Name
Roflumilast
PubChem ID
Chemical Structure
Chemical structure of roflumilast
roflumilast
InChIKey

MNDBXUUTURYVHR-UHFFFAOYSA-N

Definition (ChEBI)

A benzamide obtained by formal condensation of the carboxy group of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid with the amino group of 3,5-dichloropyridin-4-amine. Used for treatment of bronchial asthma and chronic obstructive pulmonary disease. ChEBI: Roflumilast is a benzamide obtained by formal condensation of the carboxy group of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid with the amino group of 3,5-dichloropyridin-4-amine. Used for treatment of bronchial asthma and chronic obstructive pulmonary disease. It has a role as a phosphodiesterase IV inhibitor and an anti-asthmatic drug. It is a member of benzamides, a chloropyridine, an aromatic ether, an organofluorine compound and a member of cyclopropanes.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (14)
Synonyms
162401-32-3
3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-(DIFLUOROMETHOXY)BENZAMIDE
3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
BYK20869
Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-
PubChem:449193
Roflumilast
roflumilastum
Secondary FlyBase IDs
    References (3)