FB2026_03 , released September 17, 2026
Chemical: PX-866
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General Information
Name
PX-866
FlyBase ID
FBch0002954
ChEBI Name
PX-866
ChEBI ID
CHEBI:65345
PubChem Name
Sonolisib
PubChem ID
CID:9849735
Chemical Structure
Chemical structure of PX-866
PX-866
InChIKey

QIUASFSNWYMDFS-NILGECQDSA-N

Definition (ChEBI)

An organic heterotetracyclic compound that is obtained from wortmanin via aminolysis of its furan ring by diallyl amine. ChEBI: PX-866 is an organic heterotetracyclic compound that is obtained from wortmanin via aminolysis of its furan ring by diallyl amine. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is an organic heterotetracyclic compound, a delta-lactone, an acetate ester and a tertiary amino compound. It is functionally related to a wortmannin.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (13)
Synonyms
(1E,4S,4aR,5R,6aS,9aR)-1-{[di(prop-2-en-1-yl)amino]methylidene}-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-2,7,10-trioxo-1,2,4,4a,5,6,6a,7,8,9,9a,10-dodecahydroindeno[4,5-h]isochromen-5-yl acetate
(ChEBI, 2019-)
502632-66-8
(PubChem, 2019-)
CHEBI:65345
(PubChem, 2019-)
DJM-166
(PubChem, 2019-)
PX 866
(PubChem, 2019-)
PX-866
(ChEBI, 2019-, PubChem, 2019-)
PX-866-17OH
(Bearden et al., 2024)
PX866
(PubChem, 2019-)
PubChem:9849735
(PubChem, 2019-)
SONOLISIB [WHO-DD]
(PubChem, 2019-)
Sonolisib
(PubChem, 2019-)
Sonolisib (PX-866)
(PubChem, 2019-)
Sonolisib [INN]
(PubChem, 2019-)
Secondary FlyBase IDs
    References (3)