FB2026_02 , released June 18, 2026
Chemical: C646
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General Information
Name
C646
FlyBase ID
FBch0003246
ChEBI Name
C646
ChEBI ID
CHEBI:132974
PubChem Name
4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid
PubChem ID
CID:2871948
Chemical Structure
Chemical structure of C646
C646
InChIKey

HEKJYZZSCQBJGB-UHFFFAOYSA-N

Definition (ChEBI)

A pyrazolone that is 5-methyl-4-methylene-2-(p-carboxyphenyl)-2,4-dihydro-3H-pyrazol-3-one in which the exocyclic carbon of the methylene group is attached to a 5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl group by a single bond. C646 is a potent, cell permeable and selective competitive inhibitor of p300 and CBP (p300/CBP) histone acetyltransferases.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (12)
Synonyms
328968-36-1
(PubChem, 2019-)
4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid
(PubChem, 2019-)
4-(4-{[5-(4,5-dimethyl-2-nitrophenyl)-2-furyl]methylene}-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
(ChEBI, 2019-)
C 646 compound
(PubChem, 2019-)
C-646
(PubChem, 2019-)
C-646 compound
(PubChem, 2019-)
C24H19N3O6
(PubChem, 2019-)
C646
(Long et al., 2025, ChEBI, 2019-, PubChem, 2019-)
CHEMBL4208500
(PubChem, 2019-)
PubChem:2871948
(PubChem, 2019-)
RefChem:513528
(PubChem, 2019-)
orb1305465
(PubChem, 2019-)
Secondary FlyBase IDs
    References (3)