FB2026_03 , released September 17, 2026
Chemical: ML-210
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General Information
Name
ML-210
FlyBase ID
FBch0003293
ChEBI Name
ML-210
ChEBI ID
PubChem Name
ML-210
PubChem ID
Chemical Structure
Chemical structure of ML-210
ML-210
InChIKey

VIBHJPDPEVVDTB-UHFFFAOYSA-N

Definition (ChEBI)

An <em>N</em>-acylpiperazine that is piperazine substituted by 5-methyl-4-nitro-1,2-oxazole-3-carbonyl and bis(4-chlorophenyl)methyl groups at positions 1 and 4, respectively. It is a glutathione peroxidase 4 (GPX4) inhibitor which induces ferroptosis in cancer cells expressing the RAS oncogene.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (14)
Synonyms
(4-(bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone
1360705-96-9
CHEBI:176502
CHEMBL1951048
MFCD22666407
PubChem:49766530
RefChem:1089766
[4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-methanone
[4-[bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
{4-[bis(4-chlorophenyl)methyl]piperazin-1-yl}(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
Secondary FlyBase IDs
    References (3)