The R92B11 enhancer fragment is fused upstream of the Drosophila synthetic core promoter (DSCP) followed by the p65(AD)::Zip+ hemidriver (component of a 'split driver' system, contains the p65 activation domain). A Hsp70 transcriptional terminator is present.
The R82D11 enhancer fragment is fused upstream of the Drosophila synthetic core promoter (DSCP) followed by the GAL4(DBD)::Zip- hemidriver (component of the 'Split GAL4' system, contains the GAL4 DNA-binding domain). A Hsp70 transcriptional terminator is present.
In a split-GAL4 system, HsapRELAAD.R92B11 drives expression in lobula columnar neuron LC18 when combined with ScerGAL4DBD.R82D11.
In a split-GAL4 system, ScerGAL4DBD.R82D11 drives expression in lobula columnar neuron LC10a, LC10b and LC10c when combined with HsapRELAAD.R35D04, and lobula columnar neuron LC18 when combined with HsapRELAAD.R92B11.