FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

hypomorphic allele - genetic evidence

ID (Ontology)

FBcv:0000289 (FlyBase CV)

Definition

Allele inferred to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity from the observation that extra copies in the genome decrease the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype than the allele in trans to a deletion of the gene (1 copy)).[ FlyBase:FBrf0002371 FlyBase:FBrf0049147 ]

Comment

Links to External Ontologies

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Alleles (FBal)	ALLELE_CLASS
Alleles (FBal)	PROMOTED_CLASS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Alleles
hypomorphic allele - genetic evidence (all annotations which use CV term, excluding "NOT" statements)

Spanning Tree (Parents/Children)

  loss of function allele
   |__hypomorphic allele
       |__hypomorphic allele - genetic evidence  2370 rec.
           |__temperature conditional hypomorphic allele - genetic evidence 56 rec.
               |__cold sensitive hypomorphic allele - genetic evidence 6 rec.
               |__heat sensitive hypomorphic allele - genetic evidence 49 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	hypomorphic allele
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts