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| Term | antimorphic allele - genetic evidence | ID (Ontology) | FBcv:0000292 (FlyBase CV) | |||||||||
| Definition | An allele that is inferred to make a gene product that is antagonistic to the wild-type gene product from the observations that extra copies of the wild-type allele reduce the expressivity and/or penetrance of the phenotype. So, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus. This test is similar to that used for hypomorphic alleles. An antimorph can be distinguished from a dominant hypermorph as only the former can be reverted to wild-type by deletion of the mutant allele.[ FlyBase:FBrf0002371 FlyBase:FBrf0049147 ] | |||||||||||
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gain of function allele |__antimorphic allele |__antimorphic allele - genetic evidence 256 rec. |__temperature conditional antimorphic allele - genetic evidence 5 rec. |__cold sensitive antimorphic allele - genetic evidence 3 rec. |__heat sensitive antimorphic allele - genetic evidence 2 rec. |
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| Is a | antimorphic allele | ||
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