FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

hypermorphic allele - genetic evidence

ID (Ontology)

FBcv:0000293 (FlyBase CV)

Definition

An allele inferred to make either increased amounts of a normal gene product or a gene product with normal function but increased activity compared to wild-type from the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that homozygotes (2 copies) have a stronger phenotype than transheterozygotes to a deletion of the gene (1 copy).[ FlyBase:FBrf0002371 FlyBase:FBrf0049147 ]

Comment

Links to External Ontologies

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Alleles (FBal)	ALLELE_CLASS
Alleles (FBal)	PROMOTED_CLASS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Alleles
hypermorphic allele - genetic evidence (all annotations which use CV term, excluding "NOT" statements)

Spanning Tree (Parents/Children)

  gain of function allele
   |__hypermorphic allele
       |__hypermorphic allele - genetic evidence  59 rec.
           |__temperature conditional hypermorphic allele - genetic evidence 1 rec.
               |__cold sensitive hypermorphic allele - genetic evidence
               |__heat sensitive hypermorphic allele - genetic evidence

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	hypermorphic allele
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts