FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term heat sensitive gain of function allele ID (Ontology) FBcv:0000749 (FlyBase CV)
Definition An allele that at high temperatures but not low temperatures, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.[ FlyBase:FBrf0049147 ]
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Data ClassFieldDirect annotations
Alleles (FBal)ALLELE_CLASS
Alleles (FBal)PROMOTED_CLASS
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 heat sensitive gain of function allele (all annotations which use CV term, excluding "NOT" statements)
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  gain of function allele
   |__temperature conditional gain of function allele
       |__heat sensitive gain of function allele  20 rec.
           |__heat sensitive antimorphic allele 2 rec.
           |   |__heat sensitive antimorphic allele - genetic evidence 2 rec.
           |   |__heat sensitive antimorphic allele - molecular evidence
           |__heat sensitive hypermorphic allele
           |   |__heat sensitive hypermorphic allele - genetic evidence
           |   |__heat sensitive hypermorphic allele - molecular evidence
           |__heat sensitive neomorphic allele 4 rec.
               |__heat sensitive neomorphic allele - genetic evidence 4 rec.
               |__heat sensitive neomorphic allele - molecular evidence
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Is a temperature conditional gain of function allele
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