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| Term | temperature conditional hypomorphic allele - genetic evidence | ID (Ontology) | FBcv:0000754 (FlyBase CV) | ||||||
| Definition | An allele inferred from genetic evidence to have normal activity at some temperatures (permissive temperatures) but at other temperatures to make a gene product with normal function but in a lesser amount or with lowered activity (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy)).[ FlyBase:FBrf0002371 FlyBase:FBrf0049147 ] | ||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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hypomorphic allele |__hypomorphic allele - genetic evidence________ |__temperature conditional hypomorphic allele___| temperature conditional loss of function allele | |__temperature conditional hypomorphic allele___| temperature conditional hypomorphic allele - genetic evidence 56 rec. |__cold sensitive hypomorphic allele - genetic evidence 6 rec. |__heat sensitive hypomorphic allele - genetic evidence 49 rec. |
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hypomorphic allele - genetic evidence temperature conditional hypomorphic allele |
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