FB2026_03 , released September 17, 2026
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Term binary expression system - conditional driver ID (Ontology) FBcv:0005064 (FlyBase CV)
Definition Transactivator ('driver') that forms part of a binary expression system and whose activity is regulated in response to a particular stimulus. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. Use of a conditional driver permits further refinement of this expression pattern.
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 binary expression system - conditional driver (all annotations which use CV term, excluding "NOT" statements)
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  binary expression system component
   |__binary expression system - driver
       |__binary expression system - conditional driver  16 rec.
           |__binary expression system - light-regulated driver 3 rec.
           |__binary expression system - small molecule-regulated driver 13 rec.
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