FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

binary expression system - small molecule-regulated driver

ID (Ontology)

FBcv:0005065 (FlyBase CV)

Definition

Transactivator ('driver') that forms part of a binary expression system and whose activity is regulated by binding to a small molecule, such as an ion or ligand. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. Use of a small molecule-regulated driver permits further refinement of this expression pattern.

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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Experimental Tools
binary expression system - small molecule-regulated driver (all annotations which use CV term, excluding "NOT" statements)
encodes tool \| binary expression system - small molecule-regulated driver

Spanning Tree (Parents/Children)

  binary expression system - driver
   |__binary expression system - conditional driver
       |__binary expression system - small molecule-regulated driver  13 rec.

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Is a	binary expression system - conditional driver
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Synonyms & Secondary IDs
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