Complex: CATCHR COMPLEXES

General Information

Name

CATCHR COMPLEXES

Species

D. melanogaster

Symbol

CATCHR

FlyBase ID

FBgg0000051

Date last reviewed

2026-04-15

Number of members

Description

The Complex Associated with Tethering Containing Helical Rods (CATCHR) family or DCGE group (Dsl1, COG, GARP, exocyst) are multi-subunit tethering complexes which share low sequence identity but conserved helical bundle structures. They are involved in capturing vesicles in ER-Golgi-plasma membrane trafficking. (Adapted from PMID:19575650 and FBrf0223481).

Notes on Group

In Mammals and yeast a fourth CATCHR family tethering complex has been described: the NRZ/Dsl1 complex. Such a complex has not been found Drosophila but Zw10 and Rint1 have been implicated ER-Golgi trafficking and membrane addition during cytokinesis (FBrf0219791), indicating that such a complex may exist.

Source Material

The CATCHR COMPLEXES Gene Group has been compiled using the following publication(s): Li and Blissard, 2015, Rosa-Ferreira et al., 2015, Gillingham et al., 2014, Belloni et al., 2012, Heider and Munson, 2012, and Smith and Lupashin, 2008 .

Key Gene Ontology (GO) terms

Molecular Function

Biological Process

vesicle-mediated transport

Cellular Component

Related Gene Groups

Component group(s)

CONSERVED OLIGOMERIC GOLGI COMPLEX

EXOCYST

GOLGI-ASSOCIATED RETROGRADE PROTEIN COMPLEXES

Members (21)

For all members: