Gene Group: GOLIATH UBIQUITIN LIGASES

General Information

Name

GOLIATH UBIQUITIN LIGASES

Species

D. melanogaster

Symbol

E3-GOL

FlyBase ID

FBgg0000104

Date last reviewed

2014-07-10

Number of members

Description

E3 (ubiquitin) ligases interact with both ubiquitin-E2 (ubiquitin-conjugating) enzymes and the target protein, transferring the ubiquitin from the E2 to the substrate. The Goliath (or GRAIL) E3 ligases possess transmembrane spanning domain, a protease-associated domain and a RING finger domain. (Adapted from FBrf0220873).

Notes on Group

Source Material

The GOLIATH UBIQUITIN LIGASES Gene Group has been compiled using the following publication(s): Yamazaki et al., 2013, Du et al., 2011, and Ying et al., 2011 .

Key Gene Ontology (GO) terms

Molecular Function

ubiquitin protein ligase activity

Biological Process

protein ubiquitination

negative regulation of apoptotic process

Cellular Component

Related Gene Groups

Parent group(s)

RING DOMAIN E3 UBIQUITIN LIGASES

Members (2)

For all members: