FB2026_02 , released June 18, 2026
Gene Group: NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNITS
Open Close
General Information
Name
NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNITS
Species
D. melanogaster
Symbol
NACHR
FlyBase ID
FBgg0000202
Date last reviewed
2013-08-09
Number of members
10
Description
Description
Nicotinic ligand-gated ion channels (nAChR) mediate the fast actions of the acetylcholine (ACh). The non-selective ion channel is formed from five subunits arranged around a central pore. The ACh binding site is formed by two adjacent α subunits. Other regulatory subunits may modulate channel pharmacology and expression. (Adapted from FBrf0183743).
Notes on Group
Source Material
The NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNITS Gene Group has been compiled using the following publication(s): Dupuis et al., 2012, Sattelle et al., 2005, and Littleton and Ganetzky, 2000 .
Key Gene Ontology (GO) terms
Molecular Function
acetylcholine-gated monoatomic cation-selective channel activity
Biological Process
synaptic transmission, cholinergic
Cellular Component
acetylcholine-gated channel complex
postsynaptic membrane
Related Gene Groups
Parent group(s)
ACETYLCHOLINE RECEPTORS
LIGAND-GATED ION CHANNELS
NON-SELECTIVE CATION CHANNEL SUBUNITS
Members (10)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
NACHR
NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNITS
Nicotinic receptor
nAChR
Secondary FlyBase ID(s)
References (4)