FB2026_03 , released September 17, 2026
Gene Group: 5-HYDROXYTRYPTAMINE (SEROTONIN) GPCRs
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General Information
Name
5-HYDROXYTRYPTAMINE (SEROTONIN) GPCRs
Species
D. melanogaster
Symbol
5HTR
FlyBase ID
FBgg0000206
Date last reviewed
2023-06-30
Number of members
5
Description
Description
5-hydroxytryptamine (serotonin) GPCRs belong to the Class A GPCR family. They bind and transmit the signal from the neurotransmitter 5-HT (serotonin). The family can be subdivided into seven subclasses: 5-HT1-7 based on pharmacology, signal transduction and structure. (Adapted from PMID:18571247).
Notes on Group
Source Material
The 5-HYDROXYTRYPTAMINE (SEROTONIN) GPCRs Gene Group has been compiled using the following publication(s): Hanlon and Andrew, 2015, Gasque et al., 2013, and Hauser et al., 2006 .
Key Gene Ontology (GO) terms
Molecular Function
G protein-coupled serotonin receptor activity
Biological Process
serotonin receptor signaling pathway
Cellular Component
plasma membrane
Related Gene Groups
Parent group(s)
AMINE RECEPTORS
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
5HTR
5-HYDROXYTRYPTAMINE (SEROTONIN) GPCRs
Serotonin receptor
5-hydroxytryptamine receptor
5-HT receptor
5-HTR
Secondary FlyBase ID(s)
References (4)