FB2026_02 , released June 18, 2026
Gene Group: KASH DOMAIN GENES
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General Information
Name
KASH DOMAIN GENES
Species
D. melanogaster
Symbol
KASH
FlyBase ID
FBgg0000210
Date last reviewed
2013-12-20
Number of members
2
Description
Description
The KASH domain consists of a C-terminal transmembrane domain followed by a 30 amino acid domain sequence. This domain targets the protein to the outer leaflet of the nuclear membrane by interacting with SUN domain proteins. KASH proteins are involved in mediating nuclear interactions such as with the cytoskeleton for localisation of the nucleus. (Adapted from FBrf0189793).
Notes on Group
Source Material
The KASH DOMAIN GENES Gene Group has been compiled using the following publication(s): Starr and Fischer, 2005 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
nucleus localization
Cellular Component
nuclear outer membrane
Related Gene Groups
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
KASH
KASH DOMAIN GENES
KASH domain proteins
Klarsicht ANC-1 Syne Homology domain
KLS domain
Klarsicht domain
KLS
Secondary FlyBase ID(s)
References (2)