FB2026_02 , released June 18, 2026
Gene Group: SET DOMAIN LYSINE METHYLTRANSFERASES
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General Information
Name
SET DOMAIN LYSINE METHYLTRANSFERASES
Species
D. melanogaster
Symbol
SET
FlyBase ID
FBgg0000274
Date last reviewed
2015-06-09
Number of members
15
Description
Description
SET domain lysine methyltransferases (KMTs) catalyze the addition of methyl groups to lysine residues. SET domain KMTs possess a domain that was original characterized in the D.mel KMTs Su(var)3-9, E(z) and trx. (Adapted from FBrf0216343).
Notes on Group

upSET has not been included as it lacks key amino acids required lysine methyltransferase activity (FBrf0220189).

Source Material
The SET DOMAIN LYSINE METHYLTRANSFERASES Gene Group has been compiled using the following publication(s): Jiang et al., 2017, Shilatifard, 2012, Mohan et al., 2011, Mis et al., 2006, Dillon et al., 2005, and Schotta et al., 2004 .
Key Gene Ontology (GO) terms
Biological Process
Cellular Component
Related Gene Groups
Members (15)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
SET
SET DOMAIN LYSINE METHYLTRANSFERASES
Secondary FlyBase ID(s)
References (8)