FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Complex: FACT COMPLEX
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General Information
Name
FACT COMPLEX
Species
D. melanogaster
Symbol
FACT
FlyBase ID
FBgg0000282
Date last reviewed
Number of members
2
Description
Description
FACT (facilitates chromatin transcription) is a heterodimer that destabilizes interactions between the H2A/H2B dimer and the H3/H4 tetramer of nucleosomes. FACT is involved in multiple processes such as transcription elongation, DNA replication and repair. (Adapted from FBrf0208591).
Notes on Group
Source Material
The FACT COMPLEX Gene Group has been compiled using the following publication(s): Lou et al., 2024, Tsunaka et al., 2009, Lehmann, 2004, and Shimojima et al., 2003 .
Key Gene Ontology (GO) terms
Molecular Function
nucleosome binding
Biological Process
chromatin organization
Cellular Component
FACT complex
Related Gene Groups
Parent group(s)
TRANSCRIPTION ELONGATION FACTOR COMPLEXES
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
FACT
FACT COMPLEX
Facilitates chromatin transcription complex
Secondary FlyBase ID(s)
References (5)