FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Complex: NORC COMPLEX
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General Information
Name
NORC COMPLEX
Species
D. melanogaster
Symbol
NORC
FlyBase ID
FBgg0000293
Date last reviewed
2023-08-08
Number of members
2
Description
Description
NoRC (Nucleolar remodeling complex) is an ISWI ATPase-containing complex interacts involved in repressing rDNA transcription. (Adapted from PMID:25533489).
Notes on Group

There is not yet conclusive evidence that NoRC exists in Drosophila. The heterotrimeric ToRC complex, contains two subunits orthologous to the NoRC complex. It has been speculated that an interaction with CtBP targets the dimer towards ToRC activities (Adapted from FBrf0217777).

Source Material
The NORC COMPLEX Gene Group has been compiled using the following publication(s): Emelyanov et al., 2012 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
chromatin remodeling
Cellular Component
ISWI-type complex
Related Gene Groups
Parent group(s)
ISWI COMPLEXES
Protein Complex group(s)
TORC REMODELING COMPLEX
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
NORC
NORC COMPLEX
Nucleolar remodeling complex
Secondary FlyBase ID(s)
References (2)