FB2026_03 , released September 17, 2026
Complex: CHROMATIN ASSEMBLY FACTOR 1
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General Information
Name
CHROMATIN ASSEMBLY FACTOR 1
Species
D. melanogaster
Symbol
CAF-1
FlyBase ID
FBgg0000295
Date last reviewed
Number of members
3
Description
Description
Chromatin assembly factor 1 (CAF-1) is a highly conserved three-subunit histone chaperone in eukaryotes, which facilitates chromatin assembly by depositing histone H3 and H4 onto newly synthesized DNA. CAF-1 is also implicated in epigenetic regulation. (Adapted from FBrf0222414).
Notes on Group
Source Material
The CHROMATIN ASSEMBLY FACTOR 1 Gene Group has been compiled using the following publication(s): Yu et al., 2013 and Tyler et al., 2001 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
nucleosome assembly
Cellular Component
CAF-1 complex
Related Gene Groups
Protein Complex group(s)
CHROMATIN REMODELING COMPLEXES (ATP-DEPENDENT)
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
CAF-1
CHROMATIN ASSEMBLY FACTOR 1
CAF1
Secondary FlyBase ID(s)
References (3)