FB2026_03 , released September 17, 2026
Gene Group: LSD1 FAMILY HISTONE DEMETHYLASES
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General Information
Name
LSD1 FAMILY HISTONE DEMETHYLASES
Species
D. melanogaster
Symbol
LSD1
FlyBase ID
FBgg0000310
Date last reviewed
2021-07-12
Number of members
1
Description
Description
Human LSD1 (Lysine specific demethylase 1) is the founding member of a class of enzymes that remove histone H3K4 or H3K9 modifications by an oxidative demethylation reaction in which flavin is a cofactor. (Adapted from FBrf0195283).
Notes on Group

The LSD1 FAMILY DEMETHYLASES gene group contains only one member.

Source Material
The LSD1 FAMILY HISTONE DEMETHYLASES Gene Group has been compiled using the following publication(s): Holowatyj et al., 2015, Greer and Shi, 2012, and Rudolph et al., 2007 .
Key Gene Ontology (GO) terms
Molecular Function
histone demethylase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Biological Process
post-translational protein modification
Cellular Component
nucleus
Enzymatic activity
Enzyme name (EC)
1.14.-.-
Related Gene Groups
Parent group(s)
HISTONE DEMETHYLASES
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
LSD1
Lysine specific demethylase amine oxidases
LSD1 FAMILY HISTONE DEMETHYLASES
LYSINE SPECIFIC DEMETHYLASE 1 FAMILY
Secondary FlyBase ID(s)
References (4)